The experiments were carried out on the muscle spindle (MS) that located onto the soleus muscle (SM) in the anaesthetized rats. After applying a mechanical slow stretch (SS) on the SM, the MS wasn't influenced by this stimulant and it was in a slack status. On the other hand, the MS has showed a dysfunction. The slack status of MS, it means, without electro-mechanical activity for MS that was observed in isolating MS. And this slack status of MS also was occurred by insufficient of γ-motor stimulation. With using the passive stimulating vibration on the MS-SM, again, the slack status of MS was observed. Of course, in this experiment, before that the MS was made up with passive vibration, firstly, the activation of MS was clearly observed by gs-activity. On contrary of the positive effect of  gs into MS, there wasn't a positive effect with gd-activity into MS. But, it's stated that, there was the resting discharge (RD) in the MS during slack status and the RD scale has been significantly acceptable. The MS-RD was created with both of the SS and especially by γs stimulation, though not with gd stimulation.However, it was concluded that, the changing of MS-activity could be caused with the changing length of SK.M. In this process, the MS respond was pertinent to gs-activity. Meanwhile, the activation of γs was followed by activity of MS- chain- afferent. It's seemed that, in this loop of nervo-muscular wasn't any place for activating of MS-bag fiber.

Sarcopenia, the age-related decline in skeletal muscle mass and function, is one of the main contributors to morbidity and physical disability (1). In women, menopause may contribute to sarcopenia, which not only affects very old wom-en but can also have impact on middle-aged adults (2). Changes in the gonadal hormones dur-ing the menopause transition appear to be a strong determinant of skeletal muscle mass in women. . . .

Purpose: To report visual and anatomical outcome of flap loss after LASIK surgery for correction of high myopia. Materials & Methods: Retrospective evaluation of flap loss in two eyes of two patients, a rare complication of LASIK Surgery. Case No. 1: 27 y/o woman with Ref. OD -9.75; 2.75*177 VA. CC: 20/60 KR OD: 41.86*77 39.86 * 168 & partial amblyopia due to anisometropia. Case No. 2: 38 y/o woman with Ref OD. -9.50 1.0*177 VA CC: 20/30 KR OD: 42.06*77 40.99 * 167. Results: In both patients during LASIK surgery free cap complication occurred and after Laser therapy free cap positioned over the stromal bed, but the next day after operation flaps were lost. For case NO.1only medical management performed and after 4.5 years F/U cornea has 2° central haziness. For case NO.2 another corneal flap from donor globe cut and sutured with Nylon 10/0 and after 18 months F/U cornea is clear. Conclusion: In patients with flat keratometry less than 41.0 Diopter rate of free cap are high and after laser therapy for high myopia the keratometry became more flat. If surgeon doesn't suture flap the rate of flap loss increase so for prevent of corneal haziness and corneal ectazia this evaluation suppose to perform donor corneal flap graft.